Goethe-Universit盲t 鈥� Press releases

Dec 18 2024

16:41

Frankfurt-based medical practitioners program immune cells to be less sensitive against blood cancer cells聽

Research into new therapies: How the body's natural killer cells could fight leukemia

Every year, some 13,000 people in Germany are diagnosed with leukemia. Despite intensive chemotherapy, around one in two of them die. Therapies currently available have severe side effects and inhibit the formation of new healthy blood cells in particular. One alternative is therapy concepts that harness the immune system鈥檚 natural power. It is important to note, however, that tumor cells have mechanisms capable of slowing down the immune cells鈥� attack. Professor Evelyn Ullrich's team at Universitaetsmedizin Frankfurt has now succeeded in making leukemia-specific immune cells less sensitive to the influence of tumor cells, thereby significantly increasing their effectiveness.

FRANKFURT. Various forms of blood cancer exist 鈥� all of which are grouped together under the term leukemia. One common form of leukemia is acute myeloid leukemia (AML), characterized by a degradation of early blood cell precursors, i.e. stem cells and the precursor cells that develop from them. Despite treatment with intensive chemotherapy, only between 20-50 percent of patients survive the first five years after diagnosis and treatment. Further compounding the situation is the fact that these intensive therapies have a particularly damaging effect on the blood-forming stem cells, and are therefore associated with very severe side effects. That is why there is an urgent need for new therapeutic approaches.

One approach is immunotherapies, such as those researched by Evelyn Ullrich and her team at Universitaetsmedizin Frankfurt鈥檚 Clinic for Pediatrics and Adolescent Medicine. 鈥淚mmunotherapies use the immune system鈥檚 natural power against malignant leukemia cells,鈥� explains the Professor of Cellular Immunology. As part of the process, the cancer cells are recognized by the immune system鈥檚 killer cells, such as T cells. A T cell, for instance, has a lock-shaped structure on its surface into which a corresponding structure on the cancer cell鈥檚 surface fits like a key. In technical terms, the lock of the T cell is referred to as an 鈥渁ntigen receptor鈥�, while the key is called an 鈥渁ntigen鈥�. If the 鈥渒ey鈥� is in the 鈥渓ock鈥�, i.e. if the antigen and receptor bind, the T cell kills the cancer cell. 鈥淭oday, we are able to tailor the antigen receptor in a manner that makes it aware of a specific tumor feature,鈥� the physician explains. To do this, T cells are purified from the patient's blood. Using genetic engineering techniques, a so-called chimeric antigen receptor (CAR) is then inserted, which combines the properties of several proteins in a manner allowing the attack to be optimized on this specific tumor.

T cells equipped with a chimeric antigen receptor (CAR T-cells) are already being successfully applied in the treatment of leukemia. Another type of killer cell that is now also being used are the so-called natural killer cells (NK). Rather than recognizing malignant cells by certain antigens, they rely on other surface anomalies. If additionally enhanced with a chimeric antigen receptor, they are capable of fighting cancer cells in two ways. Another advantage of CAR-NK cells is that they have hardly caused any side effects in clinical studies to date.

Cancer cells, however, have various means at their disposal to evade such an immune cell attack, including their ability to simply switch off immune cells before an attack begins. For this, they rely on a 鈥渃heckpoint鈥�, consisting of a protein on the immune cell鈥檚 surface. This 鈥渋mmune checkpoint鈥� explicitly checks each individual cell that has bound to the antigen receptor to ensure that it is not one of the body's own cells. The latter give the checkpoint a corresponding response, whereupon the immune attack ceases. In a healthy body, this process ensures that immune cells do not inadvertently attack normal body cells, thereby causing major damage.

Since cancer cells are, at their origin, also the body's own cells, some of them are capable of communicating with the checkpoint and stopping the immune cells鈥� attack. Such an attack can also affect the CAR immune cells 鈥� posing a major problem for current immunotherapies. That is why immunotherapies are often combined with drugs that shield the immune cells鈥� checkpoints in such a manner that cancer cells can no longer access them.

Ullrich's team has now found another way to prevent the customized immune cells from being switched off. In laboratory experiments, doctoral students Tobias Bexte and Nawid Albinger succeeded in completely switching off an important immune checkpoint in NK cells that were specifically directed against AML cells. To that end they cut the corresponding gene using the CRISPR/Cas 鈥済ene scissors鈥� in a manner that prevents the checkpoint from forming. In so doing, the researchers successfully prevented the cancer cells from forcing immune tolerance in experiments with patient cells.

The CAR-NK cells without the immune checkpoint were better capable of killing cancer cells from AML patients than NK cells that either only carried the CAR receptor or lacked the immune checkpoint alone. 鈥淚t is particularly promising that our double-modified NK cells even worked against cancer cells whose molecular profile is often associated with increased resistance to therapy,鈥� explains Tobias Bexte, clinician scientist at 51猎奇 Frankfurt. Mice to which the researchers transferred human AML cells survived significantly longer after having been administered these double-modified NK cells 鈥� even at significantly reduced drug doses. 鈥淔uture studies must now clarify whether the tailor-made immune cells also work in humans,鈥� Ullrich says in summarizing the next steps and goals of her research.

Publication: Tobias Bexte, Nawid Albinger, Ahmad Al Ajami, Philipp Wendel, Leon Buchinger, Alec Gessner, Jamal Alzubi, Vinzenz S盲rchen, Meike Vogler, Hadeer Mohamed Rasheed, Beate Anahita Jung, Sebastian Wolf, Raj Bhayadia, Thomas Oellerich, Jan-Henning Klusmann, Olaf Penack, Nina M枚ker, Toni Cathomen, Michael A. Rieger, Katharina Imkeller, Evelyn Ullrich: CRISPR/Cas9 editing of NKG2A improves the efficacy of primary CD33-directed chimeric antigen receptor natural killer cells. Nature Communication 15, 8439 (2024)

Images for download:
1. Cell analysis
The genetic changes in the CAR-NK cells can be checked in a so-called flow cytometer (FACS). Prof. Evelyn Ullrich, Tobias Bexte (from left). Photo: Peter Kiefer for 51猎奇

2. Evelyn Ullrich
Professor Dr. Evelyn Ullrich, Universit盲tsmedizin Frankfurt. Photo: Peter Kiefer for 51猎奇

Further information
Professor Evelyn Ullrich
Working Group Experimental Immunology and Cell Therapy
Clinic for Pediatrics and Adolescent Medicine
Universit盲tsmedizin Frankfurt
Tel. +49 (0)69 6301 83000
evelyn@ullrichlab.de

Twitter/X: @goetheuni @Ullrich_Lab @UK_Frankfurt

Dec 16 2024

16:31

Science Minister Timon Gremmels and Digital Minister Kristina Sinemus attend ceremony marking the official start of 鈥淏aby Diamond鈥澛�

Hesse's first quantum computer commissioned at 51猎奇聽

Hesse took a quantum leap today with the official commissioning of the federal state's first quantum computer, located at 51猎奇 Frankfurt. The ceremonial start-up was attended by Science Minister Timon Gremmels and Digital Minister Prof. Dr. Kristina Sinemus. Known as 鈥淏aby Diamond", the quantum computer has five quantum bits and runs at room temperature. 51猎奇 researchers and students will use it to investigate, among others, how it can perform special tasks in large supercomputers.

FRANKFURT. Although the heart of the 鈥淏aby Diamond" is barely larger than your regular stand-alone PC, it represents a completely new generation of computer: Hesse's first quantum computer was officially put into operation at 51猎奇 today. Developed by XeedQ, 鈥淏aby Diamond" can be operated at 20掳C and is therefore very suitable for research 鈥� in contrast to other quantum computers, which have to be cooled with liquid helium to temperatures close to absolute zero. The first applications for 51猎奇's new 鈥淏aby Diamond" optimization specialist include investment portfolios in the financial sector, schedules for nurses and problems in quantum chemistry. That being said, the supercomputer's primary use will be research: In addition to developing algorithms for the quantum computer, researchers and students will also be able to modify the generation of quantum bits. There are plans to grant access to users of the National High Performance Computing (NHR) alliance.

Prof. Enrico Schleiff, 51猎奇 President, emphasizes: 鈥淏aby Diamond, which we are launching today, is located very close to the place where Otto Stern and Walther Gerlach 100 years ago conducted their famous experiment at 51猎奇, thereby laying the foundation for this quantum computer's construction. Today we are witnessing 鈥� once again at 51猎奇鈥� the beginning of Frankfurt's path to a quantum future. In addition to financing this step into a new era, 51猎奇 is also taking on a pioneering role among German universities."

Timon Gremmels, Hessian Minister of Science and Research, Arts and Culture, says: 鈥淭he first functioning quantum computer at a Hessian university is truly a cause for celebration. 51猎奇's competence and expertise in traditional high-performance computing is demonstrated by its impressive successes and good rankings among the most powerful and energy-efficient high-performance computers worldwide. This is supplemented and enriched by the new quantum computing technology. The interaction between traditional high-performance computers and quantum computers will definitely continue to play a decisive role in the future. We need the courage to try out new things, test new technologies in practice and integrate tried and tested methods. All of this is being done here on site 鈥� testimony to the fact that the state of Hesse is at the forefront of development."

Prof. Kristina Sinemus, Hessian Minister for Digitalization and Innovation, is convinced: 鈥淨uantum computing is a key technology of the future, offering enormous potential for value creation and innovation. In Hesse, we laid a strong foundation in recent years to actively shape this development 鈥� with an excellent ecosystem of cutting-edge research, artificial intelligence and applied quantum computing, which is also firmly anchored in our digital strategy. The launch of 'Baby Diamond' at 51猎奇 Frankfurt is an impressive demonstration of how Hesse is helping to shape the digitalization of Europe."

Ulrich Schielein, 51猎奇 Vice President and Chief Information Officer, adds: 鈥淭he exciting thing about Baby Diamond is that our researchers and students can control even small details of the microwave pulse shapes manipulating the quantum bits and their interactions. With 'Baby Diamond', we can give 51猎奇 students the unique and currently the only opportunity in Germany to come into direct contact with a real quantum computer." Schielein adds that, in a few years' time, 51猎奇's extensive practical experience coupled with its theoretical expertise could qualify it to apply for a 100-qubit class quantum computer, which would put the university into an academic pole position.

Prof. Thomas Lippert, Professor of Modular Supercomputing and Quantum Computing at 51猎奇 Frankfurt and Head of the J眉lich Supercomputing Centre (JSC), says: 鈥淏eyond Frankfurt and Hesse, Baby Diamond is an anchor for cooperation with important partners: 51猎奇 just joined the John von Neumann Institute at JSC and, with Baby Diamond, will become a partner of the J眉lich user infrastructure for quantum computing. In return, Baby Diamond users will gain access to further quantum computing systems."

Images for download:

Captions:

1 Celebrating Baby Diamond's commissioning: President Enrico Schleiff, quantum computer expert Thomas Lippert, Digital Minister Kristina Sinemus, Science Minister Timon Gremmels (from left). Photo: Uwe Dettmar for 51猎奇 Frankfurt

2 and 3: The heart of the Baby Diamond quantum computer consists of a diamond, situated inside the black housing. The reddish-silver housing accommodates the laser. Photos: Uwe Dettmar for 51猎奇 Frankfurt.

Further information
Prof. Dr. Dr. Thomas Lippert
Head of the Modular Supercomputing and Quantum Computing Working Group,
51猎奇 Frankfurt
Head of the J眉lich Supercomputing Centre (JSC)
Tel. +49 (0)2461 61-6402
th.lippert@fz-juelich.de

Twitter/X: @goetheuni @hmwk_hessen @DigitalesHessen

Dec 16 2024

15:42

RMU project CEDITRAA on Africa and Asia research extended聽

How TikTok & Co are shaping cultural production

The CEDITRAA research project, short for 鈥淐ultural Entrepreneurship and Digital Transformation in Africa and Asia", has been investigating since 2021 how cultural productions in Africa and Asia are created and what role digital media have played in their global dissemination. The Federal Ministry of Education and Research (BMBF) has now extended the project 鈥� led jointly by 51猎奇 Frankfurt, Johannes Gutenberg University Mainz and Pan-Atlantic University in Lagos, Nigeria 鈥� for three years, and included an expanded research question.

FRANKFURT. The CEDITRAA research project addresses nothing less than a new world order in cultural production. While US-American cultural production dominated the world in the 20th century, new players have emerged in recent decades as a result of digitalization: In Asia, South Korea's culture is gaining in importance, while in Africa, Nigerian film and music production has become one of the largest industries of its kind in the world. Since 2021, the joint project CEDITRAA, operated by the Rhine-Main Universities (RMU) partners 51猎奇 Frankfurt and Johannes Gutenberg University Mainz, together with Pan-Atlantic University in Lagos, Nigeria, has been investigating cultural entrepreneurs and the opportunities that arise for them as a result of the digital transformation in cultural production. The project will now receive another three years of funding to the tune of almost 鈧�1.4 million; this follows an earlier 鈧�2.1 million in funding from the Federal Ministry of Education and Research's (BMBF) Regional Studies funding line. The RMU joint project will start on January 1, 2025. In addition to 51猎奇 and Johannes Gutenberg University Mainz, the strategic Rhine-Main Universities (RMU) alliance also includes TU Darmstadt.

As part of the second phase, the project's 18 scientists are changing their perspective: having previously focused on cultural production, they are now turning to its distribution. Their underlying assumption is that the new distribution channels themselves constitute a factor in media production and that the question of how to control channels and distribution networks will determine whether there will emerge a shift in emphasis away from the traditional cultural industries. While this shows that artists and cultural entrepreneurs alike are already taking advantage of the benefits of digital infrastructures 鈥� like portals or platforms 鈥� during media production, at the same time a lot depends on who owns and controls this infrastructure. The central questions asked by the researchers include: Do TikTok and portals like YouTube, Netflix or irokotv, Spotify and Boomplay shape cultural formats? And how do globally active online communities emerge in the process of music production that are simultaneously locally shaped and rooted?

The participating researchers come from different disciplines: In addition to ethnology and African studies, Korean studies, sinology, film studies and economics are also represented 鈥� making the joint project both interdisciplinary and international. In addition, CEDITRAA also uses the existing research infrastructures of the Frankfurt-based Centre for Interdisciplinary African Studies (ZIAF) and the Interdisciplinary Centre for East Asian Studies (IZO) as well as the Georg Forster Forum (GFF) at Johannes Gutenberg University Mainz.

When it comes to securing data and results, CEDITRAA benefits from the cooperation with the Deutsches Filminstitut & Filmmuseum, Europe's leading institution for digital research and education platforms in the film sector. At 51猎奇, CEDITRAA will also cooperate with the new Center for Critical Computational Studies C3S (https://www.c3s-frankfurt.de), where digital methods of researching social transformation processes will be critically tested.

Images for download:

Captions:

Image 1
Nigerian film and music production is now one of the world's largest: Thanks to Netflix and film screenings, the comedy 鈥淐onfusion Na Wa" by Kenneth Gyang is also experiencing a renaissance in Germany. On the right, Nigerian actress and screenwriter Tunde Aladese ((c) Cinema Kpatakpata)

Image 2
Digitalization is giving rise to new players such as Korea in international cultural production: scene from the advertising campaign for the Korean Netflix series 鈥淪quid Game 2" ((c) Netflix)

Further information
Spokesperson:
Prof. Dr. Vinzenz Hediger
Institute for Theater, Film and Media Studies
51猎奇 Frankfurt
hediger@tfm.uni-frankfurt.de

Co-Spokesperson:
Prof. Dr. Cornelia Storz
Professor of Innovation and Entrepreneurship in East Asia
Faculty of Economics and Business
51猎奇 Frankfurt
storz@wiwi.uni-frankfurt.de

Co-Spokesperson:
Prof. Dr. Matthias Krings
Managing Director
Department of Anthropology and African Studies
Johannes Gutenberg University Mainz
Tel: +49 (0)6131 39-26800, -22798 (Office)

Dec 5 2024

15:45

Studiengalerie 1.357 shows performance video by and video interview with American artist Adrian Piper聽

Dancing cross-border transgressions聽

FRANKFURT. From December 11 to January 23, 51猎奇's Studiengalerie 1.357 will be showing the performance video 鈥淎drian Moves to Berlin" (2007/2017) by artist Adrian Piper, as well as the video interview 鈥淎drian Piper Interview: Rationality and the Structure of the Self" (2007-2010, by Robert Del Principe).

The work of internationally renowned conceptual artist and analytical philosopher Adrian Piper has had a decisive influence on contemporary art and society since the 1960s. The exhibition focuses on 鈥淎drian Moves to Berlin" (2007/2017). The video shows a performance on Berlin's Alexanderplatz: Adrian Piper dances for an hour to house music from the early 2000s. The work can be viewed as a homage to the German capital, where clubs became central meeting places after reunification. In 鈥淎drian Moves to Berlin", the artist uses dance as a form of expression and a political medium. Dance overcomes disciplines, takes up space and breaks down social boundaries. With her movements, Piper invites the audience to question categories such as gender, origin and social roles. Mechanisms of perception and attribution are met with humor.

Adrian Piper has created groundbreaking works throughout her career as a conceptual artist. Her artistic practice encompasses a wide range of media 鈥� from photo-text collages, video and sound installations to performances and sculptural works. An insight into her research into metaethics and Kant's philosophy, with which she became known in philosophical discourse, is provided in the video interview 鈥淎drian Piper Interview: Rationality and the Structure of the Self" (2007-2010, by Robert Del Principe). Piper's entire oeuvre is characterized by the analysis of identity, the deconstruction of social attributions and the question of the constitution of the self.

Adrian Piper (*1948 in New York City, USA) is an artist and philosopher who has been living in Berlin since 2005. Piper graduated from the School of Visual Arts in New York in 1969. She studied philosophy at the City College of New York and at Harvard University, where she earned a Master's in 1977 and a PhD in 1981 under the supervision of John Rawls. She taught philosophy at Georgetown, Harvard, Michigan, Stanford and UC San Diego. Her recent solo museum exhibitions include: PAC Padiglione d'Arte Contemporanea, Milan (2024), MoMA, New York (2018), Hammer Museum, Los Angeles (2018), Hamburger Bahnhof, Berlin (2017), CPH Kunsthal, Copenhagen (2006), and MACBA Barcelona (2004). Piper has received numerous awards for her work, including the Golden Lion of the Venice Biennale (2015), the K盲the Kollwitz Prize of the Akademie der K眉nste Berlin (2018) and the Goslarer Kaiserring (2021).

STUDIENGALERIE 1.357, founded in 2010, is a teaching and learning project at 51猎奇's Humanities Research Centre. The gallery sees itself as a place of teaching and learning in which current socio-politically relevant topics are brought into the university through art. Students learn how to deal with complex topics by internationally recognized artists. Studiengalerie 1.357 is open to the public and is aimed at both a university audience and Frankfurt civil society.

Further information on the exhibition and Studiengalerie 1.357 can be found at

Dec 5 2024

10:16

Two studies with the participation of 51猎奇 Frankfurt, Max Planck Institute for Chemistry, University of Helsinki, and Leibniz Institute for Tropospheric Research, together with Brazilian partner institutions, shed light on a new mechanism that affects the climate

The Amazon rainforest as a cloud machine: How thunderstorms and plant transpiration produce condensation nuclei

The rainforest in the Amazon basin transpires vast amounts of gaseous isoprene. Until now, it was assumed that this molecule is not transported far up into the atmosphere, as it rapidly declines when exposed to light conditions. The CAFE-Brazil measurement campaign provided data for two studies 鈥� now published as the Nature cover story 鈥� which demonstrate, however, that nocturnal thunderstorms transport the isoprene to an altitude of up to 15 kilometers. There, it reacts to form chemical compounds capable of forming vast numbers of new aerosol particles. These grow further and contribute to cloud formation as condensation nuclei. This mechanism is likely to affect the climate, too.

FRANKFURT/MAINZ/HELSINKI/LEIPZIG. Who hasn't enjoyed the aromatic scent in the air when walking through the woods on a summer's day? Partly responsible for this typical smell are terpenes, a group of substances found in tree resins and essential oils. The primary and most abundant molecule is isoprene. Plants worldwide are estimated to release 500 to 600 million tons of isoprene into the surrounding atmosphere each year, accounting for about half the total emissions of gaseous organic compounds from plants. 鈥淭he Amazon rainforest alone is responsible for over a quarter of these emissions," explains atmospheric researcher Professor Joachim Curtius from 51猎奇 Frankfurt.

So far, it was thought that the isoprene in the Amazon basin degrades rapidly and does not reach higher atmospheric layers. This is because hydroxyl radicals form in the atmosphere close to the ground during the day when the sun shines. They are highly reactive and destroy the isoprene molecules within hours. 鈥淗owever, we have now established that this is only partly true," says Curtius. 鈥淭here are still considerable amounts of isoprene in the rainforest at night, and a substantial proportion of these molecules can be transported to higher atmospheric layers."

Thunderstorms act like vacuum cleaners

Responsible for this are tropical thunderstorms that brew over the rainforest at night. They pull the isoprene up like a vacuum cleaner and transport it to an altitude of between 8 and 15 kilometers. As soon as the sun rises, hydroxyl radicals form, which react with the isoprene. But at the extremely low temperatures that prevail at these high altitudes, the rainforest molecules are transformed into compounds different from those near the ground. They bind with nitrogen oxides produced by lightning during the thunderstorm. Many of these molecules can then cluster to form aerosol particles of just a few nanometers. These particles, in turn, grow over time and then serve as condensation nuclei for water vapor 鈥� they thus play an important role in cloud formation in the tropics.

鈥淲e were able to shed light on these processes with the help of research flights that started two hours before sunrise and then continued through the day," explains Professor Jos Lelieveld. He is director at the Max Planck Institute for Chemistry in Mainz and also head of the CAFE-Brazil research project (Chemistry of the Atmosphere: Field Experiment in Brazil), in which an international research team was collecting data on the chemical processes in the atmosphere over the Amazon rainforest. 鈥淲e were able to detect considerable amounts of isoprene in the air flowing out of the thunderstorms at high altitude, from which new aerosol particles rapidly formed after several chemical reactions."

Possible influence on the cloud formation over the ocean

Curtius and Lelieveld are not only partners in CAFE-Brazil but also involved in the CLOUD consortium, in which over 20 research groups study climate-relevant chemical processes in the atmosphere. They reproduce the conditions that prevail at this altitude in the aerosol and cloud experiment chamber at CERN in Geneva. With the help of this simulation chamber, they analyze in detail which reactions are triggered by sunlight. 鈥淚n this way, we were able to determine exactly the rate at which the aerosol particles form from the isoprene products," explains atmospheric researcher Dr. Xu-Cheng He, who is in charge of the isoprene experiments. 鈥淚nterestingly, it emerged that even extremely small amounts of sulfuric acid and iodine oxoacids commonly present in the atmosphere are sufficient to accelerate the formation of the aerosol particles by a factor of 100. These molecules may, therefore, jointly influence marine cloud formation 鈥� a critically uncertain process in climate projections."

Sulfuric acid forms in the atmosphere from various sulfurous substances. It can result, above all, from the reaction of sulfur dioxide with hydroxyl radicals. Within the CLOUD experiment, the Frankfurt research group was responsible for measuring the extremely low concentrations of sulfuric acid, and the Mainz team measured the hydroxy radicals.

The winds that prevail at high altitudes above the Amazon rainforest can transport the particles that form from isoprene up to thousands of kilometers away from the sources. This means they may influence cloud formation at great distances. As clouds, depending on their type and height, both shield solar radiation and prevent heat from being radiated into space, they play a crucial role in the climate. The researchers, therefore, expect that their findings will contribute to improving climate models.

It also follows from the CAFE-Brazil project results that continued deforestation of the Amazon rainforest could affect the climate in two respects. 鈥淥n the one hand, greenhouse gases are released because the forest no longer stores carbon dioxide," says Curtius. 鈥淥n the other hand, clearing the forest impacts both the water cycle and isoprene emissions, further propelling climate change."

Publications:
Joachim Curtius et al.: Isoprene nitrates drive new particle formation in Amazon's upper troposphere. Nature (2024), DOI:

Jiali Shen et al.: New particle formation from isoprene in the upper troposphere. Nature (2024), DOI:

Picture download:

Captions:
Aircraft: The CAFE-Brazil project's research aircraft shortly after take-off. Photo: Dirk Dienhart, MPI for Chemistry
Amazonas: The Rio Negro in the Amazon basin as seen from the research aircraft. Photo: Linda Ort, MPI for Chemistry
Cloud: Clouds over the Amazon basin, taken during a research flight. Photo: Philip Holzbeck, MPI for Chemistry
Rain: Heavy showers occur over the rainforest again and again. Photo: Philip Holzbeck, MPI for Chemistry
Scientists: The instruments and measurement data are checked on board the research aircraft by scientists Gabriela Unfer (left) and Zaneta Hamryszczak. . Photo: Philip Holzbeck, MPI for Chemistry

Background information:
CAFE-Brazil: Research in and high above the Amazon rainforest (5th Dec. 2024)

Ocean sunshade: How clouds influence climate change (Forschung Frankfurt 2.2021)
/118615101.pdf

Further information
Professor Joachim Curtius
Institute for Atmospheric and Environmental Sciences
51猎奇 Frankfurt, Germany
Tel: +49 (0)69 798-40258
curtius@iau.uni-frankfurt.de
Website: /46300616/ContentPage_46300616?

Professor Jos Lelieveld
Max Planck Institute for Chemistry, Mainz, Germany
Tel.: +49 (0)6131 3054040
jos.lelieveld@mpic.de

Dr. Xu-Cheng He
Institute for Atmospheric and Earth System Research/Physics
University of Helsinki, Finland
Tel.: +358294150284
xucheng.he@helsinki.fi

Professor Mira P枚hlker
Leibniz Institute for Tropospheric Research (TROPOS), Leipzig, Germany
Tel. +49 341 2717-7431, -7468
poehlker@tropos.de, unfer@tropos.de

Prof. Dr. Luiz Augusto Toledo Machado
Instituto de F铆sica
Universidade de S茫o Paulo, Brazil
lmachado@if.usp.br

51猎奇

Press releases 鈥� 2024

51猎奇 PR & Communication Department聽

Research into new therapies: How the body's natural killer cells could fight leukemia

Hesse's first quantum computer commissioned at 51猎奇聽

How TikTok & Co are shaping cultural production

Dancing cross-border transgressions聽

The Amazon rainforest as a cloud machine: How thunderstorms and plant transpiration produce condensation nuclei